Possible increased tendency to thrombosis after cerebral angiography

Abstract
Two patients are presented in whom cerebral angiography was complicated by bioccipital infarcts, resulting in cortical blindness with persisting severe restriction of the visual field (case 1) and persisting cortical blindness (case 2). One patient (case 1) demonstrated a compensated, protracted disseminated intravascular coagulation which disappeared after treatment with phenprocoumon (Marcoumar). The other patient (case 2) demonstrated increased spontaneous platelet aggregation which was treated successfully with acetylsalicylic acid (Magnyl) and dipyridamole (Persantine). The angiography was apparently pathogenetic to the coagulation disturbance complications. Coagulation studies should be performed on patients with transient cerebral ischemia and apoplexy before and after the cerebral angiography so that coagulation disturbances may be detected and treated as necessary.