Antibacterial Activity of Lactoperoxidase Adsorbed by Human Salivary Sediment and Hydroxyapatite
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in Caries Research
- Vol. 11 (5) , 257-262
- https://doi.org/10.1159/000260277
Abstract
Lactoperoxidase was shown to be adsorbed by human salivary sediment and hydroxyapatite. Phosphate ions (0.5 M) effectively regained the adsorbed activity while sodium fluoride (1 mg/l) was less effective. 45% of the total activity was adsorbed by salivary sediment in whole saliva solution and 64% in distilled water. In case of hydroxyapatite the respective values were 97 and 93%. The adsorbed peroxidase was shown to be antibacterial in the presence of cofactors, SCN–– ions and H2O2. The complete lactoperoxidase system inhibited remarkably the acid production of dental plaque when compared with the control.Keywords
This publication has 5 references indexed in Scilit:
- Xylitol-Induced Increase of Lactoperoxidase ActivityJournal of Dental Research, 1976
- Purification and characterization of the salivary antibacterial factor (S.A. Factor)Archives of Oral Biology, 1966
- STUDIES ON ANTIBACTERIAL ACTION OF HUMAN SALIVA .3. COFACTOR REQUIREMENTS OF A LACTOBACILLUS BACTERICIDIN1963
- Anti-Streptococcal Activity of Lactoperoxidase III.Experimental Biology and Medicine, 1962
- Characterization of an antibacterial factor in human parotid secretions, active against Lactobacillus caseiArchives of Oral Biology, 1962