Nephron Number, Renal Function, and Arterial Pressure in Aged GDNF Heterozygous Mice
- 1 February 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Hypertension
- Vol. 41 (2) , 335-340
- https://doi.org/10.1161/01.hyp.0000050961.70182.56
Abstract
The loss of one allele for glial cell line–derived neurotrophic factor (GDNF) results in ≈30% fewer but normal sized glomeruli in young mice. Low nephron number, inherited or acquired, has been lin...Keywords
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