Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X chromosome

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Abstract
The X chromosome region 9F12-10A7 (7 bands removed by Df(1)v l3) was saturated with lethal, semi-lethal, visible and male sterile mutations. A total of 11 complementation groups were found. In the more narrow interval of Df(1)v l1 which removes 3 bands (10A1-2, 10A3, 10A4-5) 6 loci were localised. — The band 10A1-2 consists of a sereis of 5 different subunits: (i) silent DNA where no functions were found — at the distal edge of the band; (ii) and (iii) two genes: v and 1(1)BP4; (iv) silent DNA in middle of the band, (v) locus sev on the proximal edge of the band. About 70% of the band's DNA was found to be silent. — Using the set of chromosome rearrangements removing different parts of the band it was shown that these five sequences may function independently from each other.