Eosinophil Granules and Cell Maturity: Electron Microscopic Observations on Guinea-Pig Marrow

Publisher Website
Google Scholar
Abstract
Data has been obtained relating to the granules of 3 development categories of eosinophil leukocyte, as seen in electron micrographs of guinea-pig bone marrow. Granule counts indicated that the mare mature the cell, the greater was the proportion of granules showing an internum in any particular section. Measurements of the dimensions of the largest granule-profiles also suggested that the granules without interna may be fewer or smaller (or both) in the more mature forms of cell. They further indicated that the largest profiles of internum-containing granules were, on average, more ovoid than those of the granules showing no internum. The possible functional significance of the findings was discussed.