Effect of leptin on arterial thrombosis following vascular injury in mice.
Open Access
- 3 April 2002
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 287 (13) , 1706-1709
- https://doi.org/10.1001/jama.287.13.1706
Abstract
Obesity is an independent risk factor for the complications of atherosclerotic vascular disease, such as myocardial infarction and stroke.1 Since these complications are due to acute thrombosis,2 the development of obesity may elicit a prothrombotic state. Alterations in coagulation and fibrinolytic factors with the development of obesity have been described,3-5 but causal relationships with these factors and the development of thrombosis have not been established in obesity.Keywords
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