The T9176G mutation of human mtDNA gives a fully assembled but inactive ATP synthase when modeled inEscherichia coli

Abstract
A new mutation in human F1F0 ATPase6, T9176G, which changes Leu 217 to an Arg, has been described in two siblings with Leigh syndrome [Carrozzo et al. (2000) Neurology, in press]. This mutation was m...