Host Modification of Chlamydiae: Presence of an Egg Antigen on the Surface of Chlamydiae Grown in the Chick Embryo
- 1 May 1979
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 112 (1) , 61-66
- https://doi.org/10.1099/00221287-112-1-61
Abstract
Egg-grown chlamydiae (EGO) have a yolk sac antigen associated with their surface which is absent from cell monolayer-grown organisms (CGO). EGO infectivity was specifically neutralized by rabbit antiserum to normal yolk sac; CGO infectivity before or after incubation with normal yolk sac material was not neutralized. Treatment of EGO with Clostridium welchii [C. perfringens] culture filtrate containing phospholipase C abolished spontaneous infectivity for monolayers and neutralization by anti-yolk sac antiserum but did not affect centrifuge-assisted infectivity. The possible significance of host antigen on the chlamydial surface is considered.This publication has 1 reference indexed in Scilit:
- Infectivity Titration of Guinea-pig Inclusion Conjunctivitis Agent in Irradiated McCoy CellsJournal of General Microbiology, 1976