BROMINATION OF STEROID 20-KETALS
- 1 February 1959
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 37 (2) , 345-350
- https://doi.org/10.1139/v59-044
Abstract
Bromination of 3α,12α-diacetoxypregnan-20-one ethylene ketal provided in good yield the corresponding 21-monobromo compound. This product, on acid hydrolysis and subsequent acetolysis, gave the known 3α,12α,21-triacetoxypregnan-20-one. Acid hydrolysis of the bromoketal, followed by Faworsky rearrangement, led to 3α,12α-diacetoxy-17α-methyletiocholanic acid methyl ester.Keywords
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