Glycerol as a Phosphatidyl Choline Precursor in the Developing Mammalian Lung

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Abstract
In vitro evidence demonstrates that glycerol is actively incorporated by the developing mammalian lung into phosphatidyl choline (PC synthesis) and such incorporation is a good indicator of newly synthesized PC. Morphologic evidence is also presented which shows that circulating glycerol can be used for de novo synthesis of PC and strengthens the hypothesis that circulating glycerol in the immediate postpartum adaptive period may contribute significantly to pulmonary phosphatidyl choline synthesis and thus to alveolar stability.

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