Dietary vitamin a and cancer—a Multisite case‐control study
- 1 January 1986
- journal article
- other
- Published by Taylor & Francis in Nutrition and Cancer
- Vol. 8 (2) , 107-116
- https://doi.org/10.1080/01635588609513883
Abstract
The relationship between an index of dietary vitamin A and cancer risk at 25 sites was assessed in retrospective case‐control studies. Common control groups for males and females were used in all analyses. Relative risk estimates were derived from multiple logistic regression analyses that controlled for age, alcohol consumption, and smoking exposure. We found that among males, dietary vitamin A is associated with lower risk for cancers of the tongue, floor and other mouth, pharynx, larynx, esophagus, and lung but higher risk for Hodgkin's disease and leukemia. Among females, we found that dietary vitamin A had less effect on risk generally but was associated with lower risk for bladder cancer. These findings are consistent with previous research that showed dietary vitamin A to be associated with decreased risk of squamous epithelial cancers. The association of dietary vitamin A and increased risk of Hodgkin's disease and leukemia among males in addition to the disparity in effect of dietary vitamin A on risk between males and females are areas worthy of further research.Keywords
This publication has 17 references indexed in Scilit:
- Vitamin A and Retinoids in Health and DiseaseNew England Journal of Medicine, 1984
- Diet and Cancer – An OverviewNew England Journal of Medicine, 1984
- Dietary Carcinogens and AnticarcinogensScience, 1983
- Dietary habits and lung cancer riskInternational Journal of Cancer, 1983
- Chemical CarcinogenesisNew England Journal of Medicine, 1981
- DIETARY VITAMIN A AND RISK OF CANCER IN THE WESTERN ELECTRIC STUDYThe Lancet, 1981
- Can dietary beta-carotene materially reduce human cancer rates?Nature, 1981
- THE VITAMIN A‐ZINC CONNECTION: A REVIEWAnnals of the New York Academy of Sciences, 1980
- Comparison of dietary histories in lung cancer cases and controls with special reference to vitamin ANutrition and Cancer, 1980
- Dietary vitamin a and human lung cancerInternational Journal of Cancer, 1975