Biosynthesis of oleanene- and ursene-type triterpenes from [4-13C]mevalonic acid in tissue cultures of Isodon japonicus Hara
- 1 January 1975
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 8,p. 270-271
- https://doi.org/10.1039/c39750000270
Abstract
On the basis of the 13C-labelling patterns elucidated by 13C n.m.r. spectroscopy in oleanene- and ursene-type triterpenes (1)–(5) isolated from Isodon japonicus tissue cultures fed with [4-13C]mevalonic acid, Ruzicka's hypothesis for cyclisation of squalene 2,3-oxide to the pentacyclic triterpenes has been verified experi-mentally.Keywords
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