The influence of injected cyclic AMP protein kinase catalytic subunit on the sodium efflux in barnacle muscle fibres

1 December 1982

journal article
research article
Published by Wiley in The Journal of Physiology

Vol. 333 (1) , 39-52
https://doi.org/10.1113/jphysiol.1982.sp014437

Abstract

A study has been made of the response of the Na efflux in single barnacle muscle fibers to the injection of cAMP protein kinase catalytic subunit (CSU). Injected CSU stimulates the Na efflux in unpoisoned and ouabain-poisoned fibers. Stimulation in both situations is always sustained, and stimulation of the ouabain-insensitive Na efflux is observed with as low a concentration as 10-7 M-CSU. CSU behaves as a modulator of the ouabain-insensitive Na efflux. Mg2+, Fe and Zn are inhibitors of the catalytic reaction.

This publication has 26 references indexed in Scilit:

Stimulation by injected guanosine triphosphate of the sodium efflux in barnacle muscle fibres.
The Journal of Physiology, 1982
Stimulation by high external potassium of the sodium efflux in barnacle muscle fibers
The Journal of Membrane Biology, 1981
Stimulation by injected guanosine triphosphate of the sodium efflux in barnacle muscle fibres pre‐exposed to aldosterone.
The Journal of Physiology, 1981
The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities
European Journal of Biochemistry, 1981
Cyclic AMP modulation of a specific ion channel in an identified nerve cell: possible role for protein phosphorylation.
1981
ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. I. Purification of the enzyme and its regulation by the interaction with an activating protein factor.
Journal of Biological Chemistry, 1980
The mechanism of activation of bovine skeletal muscle protein kinase by adenosine 3‘:5‘-monophosphate.
Journal of Biological Chemistry, 1980
Mode of stimulation by injection of cyclic AMP and external acidification of the sodium efflux in barnacle muscle fibres.
The Journal of Physiology, 1979
An investigation of sodium transport in barnacle muscle fibres by means of the microsyringe technique
The Journal of Physiology, 1972
Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
1969