HYPOCRELLIN, FROM HYPOCRELLA BAMBUASE, IS PHOTOTOXIC TO HUMAN IMMUNODEFICIENCY VIRUS
- 1 September 1994
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 60 (3) , 253-255
- https://doi.org/10.1111/j.1751-1097.1994.tb05100.x
Abstract
Hypocrellin, a photodynamic perylene quinonoid isolated from the Chinese medicinal fungus Hypocrella bambuase, was evaluated for antiviral activity against the human immunodeficiency virus (HIV-1). Hypocrellin was phototoxic to HIV-1, almost as good as the structurally similar plant pigment hypericin, and like hypericin its activity required visible light. In contrast peroxyhypocrellin had little or no effect on the virus.Keywords
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