AGRANULOCYTIC ANGINA

Abstract
Agranulocytic angina was first reported by Schultz1in 1922. In June, 1927, Kastlin2reported two cases and reviewed forty-one previously reported. Since Kastlin's monograph, Linthicum3has reported two cases and Finnegan4one. Of the forty-seven cases reported (including the one given below), forty-three (91 per cent) terminated fatally. Thirty-seven (78 per cent) occurred in females, the majority of whom were past the age of 40. In only one case was there a history of a previous attack. The disease is characterized by an acute onset with a temperature of from 101 F to 105 F., with great prostration, sore throat or mouth and severe headache. It is sometimes accompanied by chills, general muscle pains, vomiting, herpes, bleeding from the oral and vaginal mucosa and jaundice. A membrane is usually present either in the region of the tonsils or along the gingival margins. In the fatal jases, the external genitalia are

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