Antibiotics from Basidiomycetes. V. Merulidial, a new antibiotic from the Basidiomycete Merulius tremellosus Fr.
- 1 January 1978
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 31 (8) , 737-741
- https://doi.org/10.7164/antibiotics.31.737
Abstract
Merulidial, a new antibiotic, was isolated from the culture fluid of the Basidiomycete M. tremellosus Fr., strain No. WQ 568. Merulidial inhibits a variety of bacteria and fungi. In cells of the ascitic form of Ehrlich carcinoma, DNA synthesis is inhibited at lower concentration as compared to RNA and protein synthesis. Merulidial shows mutagenicity when incubated with the his--mutant TA 100 for Salmonella typhimurium (B.N. Ames). The molecular formula as determined by high resolution mass spectrometry is C15H20O3.This publication has 1 reference indexed in Scilit:
- The strobilurins - New antifungal antibiotics from the basidiomycete Strobilurus tenacellus.The Journal of Antibiotics, 1977