Cognitive Functioning under Moderate and Low Dosage Methadone Maintenance

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Abstract
The Wechsler Adult Intelligence Scale (WAIS) was administered to 2 groups of patients [heroin addicts] in the Santa Clara County [California, USA] Methadone Maintenance Program who were receiving low and moderate daily stabilized dosages of methadone hydrochloride. In the 2 separate statistical analyses performed, there were no significant differences found between subtest scores or verbal, performance and full-scale scores of the groups measured. These results, combined with observations regarding the similarities of WAIS profiles of the 2 groups, indicate that cognitive functioning as measured by the WAIS was not differentially affected by the 2 dosages.

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