Studies of Adipose Tissue in Man

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Abstract
A method is described for simple, virtually painless sampling of adipose tissue in man. Such samples (0 to 34.3 mg. in size) have been obtained from 145 subjects and analyzed for fatty acid composition by gas-liquid chromatography. In this way, a typical or "normal" pattern of adipose fatty acid composition in healthy, young adults has been established. Small groups of older, healthy persons as well as those with coronary artery disease, obesity and diabetes have shown no marked differences from the average pattern of healthy younger subjects. But, newly born premature and term infants have distinctive alterations. Furthermore, controlled dietary manipulations in adult life can give rise to slow changes in adipose composition. The possible significance of these findings is discussed.

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