Coronary Insufficiency Associated with Oral Administration of Gall-Bladder Dye

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Abstract
IN January, 1949, a patient who was known to have arteriosclerotic heart disease was admitted to the Veterans Administration Hospital in West Roxbury, Massachusetts, for determination of the cause of blood-streaked stools. During investigation of the gastrointestinal system a gall-bladder series was scheduled, and the dye administered. He died suddenly twelve hours later of what appeared to be acute coronary insufficiency. Interest in this patient was revived when a second fatal case occurred in a like manner some three months later. In the succeeding eight years 2 more cases of coronary inadequacy have been observed after ingestion of gall-bladder dye; . . .