Asymmetry currents in intracellularly perfused squid giant axons

Abstract
Asymmetry currents were recorded from intracellularly perfused squid axons subjected to exactly equal positive and negative voltage clamp pulses at a temperature close to 0 °C. The voltage and time dependence of the asymmetry currents was studied at a holding potential of — 80 to — 100 mV. The effect of varying the holding potential was investigated. The latter experiments showed that the voltage dependence of the asymmetrical charge movement is different from the voltage dependence of the m system.