Pattern of blood polyamines in healthy subjects from infancy to the adult age

Publisher Website
Google Scholar
Abstract
Blood polyamine levels have been determined in 161 healthy subjectsfrom newborn to adult age. During the growth period spermidine and spermine concentrations are always higher than in adulthood. In the first days of life a typical pattern for spermidine and spermine appeared with an early increase in the first hours after birth and a maximum at 24 h; afterwards the levels of both amines gradually and progressively decreased. The levels reached by 10 days of life were mantained until adulthood, at which time a further decrease was evident. The high levels of polyamines during the period of body growth may suggest that also in humans these substances play a role in the process of cellular proliferation.

This publication has 17 references indexed in Scilit: