Eine neue Synthese von Muscon und Exalton®. Die Enamin‐Route der Ringerweiterungsreaktion

Publisher Website
Google Scholar
Abstract
A New Synthesis of Muscone and Exaltone®. The Enamine Approach of Ring‐Enlargement ReactionKey reaction in the synthesis of the title compounds is the treatment of the aldehydes 6 and 7 (obtained from 1) with a primary amine, e.g. pentylamine, in EtOH at room temperature. After stirring overnight, the products 8 and 9, respectively, are obtained in good yields. Both are enlargement by three ring members and can be transformed to Exalton® (12) and (±)‐muscone, (13), respectively.