ADRENAL INSUFFICIENCY SECONDARY TO MASSIVE CORTICOMEDULLARY JUNCTION HEMORRHAGE FOLLOWING HYPOTENSION IN 3 ANTICOAGULATED PATIENTS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 5  (3) , 291-297
Abstract
Three patients treated by anticoagulation therapy sustained massive bilateral adrenal hemorrhages. In each instance, an episode of hypotension preceded the onset of the terminal course. In 2 patients death was attributable to acute Addisonian crisis. Hypotension commonly produces necrosis of the adrenal corticomedullary junction, which normally heals by fibrosis, but in the anticoagulated patient, this necrosis may be complicated by hemorrhage.

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