DEVELOPMENT OF INDUSIUM GRISEUM .2. SEMITHIN LIGHT MICROSCOPIC AND ELECTRON-MICROSCOPIC STUDY
- 1 January 1978
- journal article
- research article
- Vol. 125 (MAR) , 433-445
Abstract
Neurogenesis and gliogenesis in the indusium griseum of mice were studied in semithin sections and by EM. Immature neurons were present at birth, but differentiated rapidly until, by 15 days, they appeared to be fully differentiated. At birth 38% of glia were glioblasts, 47% were immature astrocytes and 15% were mature microglia. Astrocyte differentiation appeared to occur earlier than in adjacent white matter. In the adult, 57% of glia were astrocytes, 21% were oligodendrocytes and 22% were microglia. The volume density of neuronal nuclei did not change with age, but the volume density of neuronal perikaryon decreased from 34% at birth to 13% at 15 days while the neuropil increased from 24 to 58%. Very few immature synapses were present at birth, but by 5 days a number of axodendritic synapses were present, and these increased with age.This publication has 20 references indexed in Scilit:
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