Biosynthesis of Trichothecene Mycotoxins in Fusarium culmorum Cultures
Open Access
- 1 July 1985
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C
- Vol. 40 (7-8) , 514-518
- https://doi.org/10.1515/znc-1985-7-810
Abstract
A high yielding production of the trichothecene mycotoxin 3-acetyldeoxynivalenol (3-AcDON) in cultures of F. culmorum is described. By supplying [14C]acetate, 14C-labeled 3-AcDON suitable for further metabolic studies was obtained. The pattern of labeling was ascertained by using 13C-labeled acetate precursors and is in line with established biosynthetic data. A second trichothecene produced in significant amounts by F. culmorum was identified as 3.alpha.,15-diacetoxy-7.alpha.,8.alpha.-dihydroxyl-12,13-epoxytrichothec-9-ene (7.alpha.,8.alpha.-dihydroxycalonectrin).Keywords
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