Abstract
Obesity is associated with increased morbidity and mortality. The condition, and central obesity in particular, is linked to a number of disorders including glucose intolerance, insulin resistance, hyperinsulinaemia, hypertension, dyslipidae-mia, impaired fibrinolysis, atherosclerosis, gall bladder disease, some cancers and osteoarthritis. Weight loss therefore benefits the individual by reducing health risks and improving the quality of life. A body mass index (BMI) of around 22 kg/m2 is related to a minimal risk of mortality compared with higher BMI values. An extensive review of clinical studies has shown the clear benefits of moderate weight loss (5-10% of baseline body weight). Thus in obese individuals for whom a substantial weight loss is not feasible, moderate weight loss should be encouraged.

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