Synthesis of optically active trifluorinated compounds: asymmetric Michael addition with hydrolytic enzymes
- 1 January 1986
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 17,p. 1331-1333
- https://doi.org/10.1039/c39860001331
Abstract
Syntheses of optically active compounds possessing a trifluoromethyl group, via enzymatic chiral Michael addition reaction of 2-(trifluoromethyl)propenoic acid and synthesis of trifluoromethylated heterocycles, have been under-taken.Keywords
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