THE COLLECTION AND PREPARATION OF HUMAN-BLOOD PLASMA OR SERUM FOR TRACE-ELEMENT ANALYSIS

1 March 1986

journal article
Published by National Institute of Standards and Technology (NIST) in Journal of Research of the National Bureau of Standards

Vol. 91 (2) , 87-92
https://doi.org/10.6028/jres.091.014

Abstract

Trace element concentrations in blood plasma or serum have been assayed by numerous investigators using a variety of analytical techniques. For several elements, figures obtained in different centers are widely disparate. Impressive evidence has accumulated that a great deal of the inconsistencies should be ascribed to unsuspected contamination of the samples with exogenous material during their collection and preparation. In this paper, a number of potential sources of extraneous additions are indicated. Methods for controlling contamination are also briefly discussed.

Keywords

BLOOD COLLECTION DEVICES
CLEAN ROOM CONDITIONS
HIGH-PURITY REAGENTS
SAMPLE CONTAINERS
SAMPLE CONTAMINATION

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