Effects of diuretics on microsomal (Na+, K+)-ATPase in the human heart and the rat heart and kidney
- 1 July 1970
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 4 (3) , 343-347
- https://doi.org/10.1093/cvr/4.3.343
Abstract
Mercurial and oral diuretics act as non-competitive inhibitors of human and rat myocardial microsomal (Na+, K+)-ATPase in vitro. The in vivo administration of such diuretics did not change (Na+, K+)-ATPase activity in the rat heart or kidney.Keywords
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