Perineurium: Evidence for Contractile Elements

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Abstract
Electron-microscopic study of mouse sciatic nerve reveals that perineurial cells contain filaments and associated opaque regions similar to those observed in smooth muscle. This finding is consistent with obsevations Which suggest that nerve might have a contractile property. In addition to their function in maintaining the connective tissue stroma of perineurium, as well as being a selective diffusion barrier, perineurial cells may serve the nerve in a contractile capacity.