(R)-(--)-1,1-Diphenyl-3-piperidinobutan-1-ol, an Anticholinergic Agent. The Crystal Structure of (R)-(--)-1,1-Diphenyl-3-piperidiniobutan-1-ol (R,R)-tartrate.
- 1 January 1990
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 44 (3) , 284-287
- https://doi.org/10.3891/acta.chem.scand.44-0284
Abstract
Racemic 1,1-diphenyl-3-piperidinobutan-1-ol has been prepared and optically resolved employing (R,R)- and (S,S)-tartaric acid, respectively, as the resolving agents. The absolute configurations of the enantiomers have been established as (R)-(-) and (S)-(+) by a crystal structure analysis of (R)-(-)-1,1-diphenyl-3-piperidiniobutan-1-ol (R,R)-tartrate.This publication has 1 reference indexed in Scilit:
- Stereoselectivity of the enantiomers of trihexyphenidyl and its methiodide at muscarinic receptor subtypesEuropean Journal of Pharmacology, 1988