Peterson (Silyl-Wittig) Methylenation of Carbonyl Compounds Using Nation-H® Catalyzed Hydroxy-Trimethylsilane Elimination of β-Hydroxysilanes
- 1 January 1991
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1991 (01) , 29-30
- https://doi.org/10.1055/s-1991-26371
Abstract
The Peterson (silyl-Wittig) methylenation of carbonyl compounds is significantly improved by convenient hydroxy-trimethylsilane elimination of the intermediate ß-hydroxysilanes using perfluoroalkanesulfonic acid (Nafion-H®) catalysis. These high yield reactions proceed at room temperature, and the workup involves only filtration of the catalyst.Keywords
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