ENDOCRINE EFFECTS OF LITHIUM:

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Abstract
Manic-depressive patients (96) were studied during long-term Li treatment. Highly significant elevations were observed respecting the levels of serum immunoreactive parathyroid hormone (P < 0.001) as well as the protein-corrected levels of serum Ca (P < 0.001) and serum Mg (P < 0.001), thus indicating a state of primary hyperparathyroidism. The patients as a group had normophosphatemia and normophosphatasis supporting the impression of a rather mild state of biochemical hyperparathyroidism.