Montelukast, a Leukotriene-Receptor Antagonist, for the Treatment of Mild Asthma and Exercise-Induced Bronchoconstriction
Open Access
- 16 July 1998
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 339 (3) , 147-152
- https://doi.org/10.1056/nejm199807163390302
Abstract
Patients with mild asthma frequently have only exercise-induced bronchoconstriction, a symptom of inadequate control of asthma. We evaluated the ability of montelukast, a leukotriene-receptor antagonist, to protect such patients against exercise-induced bronchoconstriction.Keywords
This publication has 20 references indexed in Scilit:
- Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D 4–receptor antagonist cinalukastJournal of Allergy and Clinical Immunology, 1997
- Inhibition of exercise-induced bronchospasm by zileuton: a 5-lipoxygenase inhibitor.American Journal of Respiratory and Critical Care Medicine, 1996
- The effect of regular inhaled albuterol on exercise-induced bronchoconstriction.American Journal of Respiratory and Critical Care Medicine, 1996
- Rapid Onset of Tolerance to the Bronchoprotective Effect of SalmeterolChest, 1995
- Standardization of Spirometry, 1994 Update. American Thoracic Society.American Journal of Respiratory and Critical Care Medicine, 1995
- Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4receptor antagonistCanadian Journal of Physiology and Pharmacology, 1995
- Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterolRespiratory Medicine, 1994
- The Protective Effect of Inhaled Leukotriene D4Receptor Antagonist ICI 204,219 against Exercise-induced AsthmaAmerican Review of Respiratory Disease, 1993
- Urinary leukotriene E4 after exercise challenge in children with asthmaJournal of Allergy and Clinical Immunology, 1992
- Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D4–Receptor AntagonistNew England Journal of Medicine, 1990