Validation of cardiac output estimates by digital video subtraction angiography in dogs. Correlation with thermodilution values.

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Abstract
To determine the validity of cardiac output estimates obtained by digital video subtraction angiography (DVSA), the estimates were compared with thermodilution values in 6 anesthetized dogs. Multiple levels of cardiac output were produced in each dog by graded openings of peripheral arteriovenous fistulas. Both direct contrast and mask-mode images were evaluated. There was good correlation bewtween thermodilution and direct constrast values (r = 0.88), as well as between thermodilution and mask-mode values (r = 0.89), though the mask-mode outputs were 12 .+-. 1.1% < the direct contrast values (P < 0.05). Direct contrast and mask-mode values correlated well (n = 6; r .gtoreq. 0.95). Digital outputs exhibited little variation, indicating excellent reproducibility. The validity of area-length estimates of caridac output by DVSA is demonstrated.

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