THE EFFECT OF ADRENAL CORTICAL EXTRACT ON THE RESISTANCE OF NON-ADRENALECTOMIZED RATS TO PEPTONE SHOCK
- 1 September 1944
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 142 (2) , 191-194
- https://doi.org/10.1152/ajplegacy.1944.142.2.191
Abstract
Normal rats were caused to develop shock by the intraperit. inj. of a 50% soln. of peptone. A comparison, was made in the incidence of survival to 48 hrs. of rats which were treated with cortical extracts, 11-desoxycorticosterone acetate and rats given control solns. The inj. of large doses of cortical extracts increased the incidence of survival over that of untreated animals. Extracts derived from hog adrenal glands were superior to extracts of beef adrenal glands. The adm. of 11-desoxycorticosterone acetate and of small doses of adrenal cortical extracts were ineffective.This publication has 2 references indexed in Scilit:
- THE RÔLE OF THE ADRENAL CORTEX IN PHYSIOLOGICAL PROCESSESPhysiological Reviews, 1944
- THE SURVIVAL OF NON-ADRENALECTOMIZED RATS IN SHOCK WITH AND WITHOUT ADRENAL CORTICAL HORMONE TREATMENTAmerican Journal of Physiology-Legacy Content, 1943