Comments on estimations of risks to translocation carriers

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Abstract
Two projects for estimation of risks to carriers of reciprocal translocations based on data from more than 1,100 families are compared. The 2 projects differ considerably with regard to the amount of information utilized in the data, the statistical methods used—either standard computer programs or methods specially developed for the data—and the relevance and variety of the obtained results. The comparison shows the strength of utilizing tailor‐made statistical methods for extracting relevant information from available data in human genetics instead of statistical standard methods from general computer programs.