Synthesis of oligodeoxyribonucleotides by a continuous-flow, solid-phase method using phosphotriester intermediates

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Abstract
A new composite polydimethylacrylacrylamide–kieselguhr support has been used in a continuous-flow assembly apparatus for the efficient solid-phase synthesis of an undeca- and a heptadeca-deoxyribonucleotide using phosphotriester intermediates.