Immunological Characterization of an Ocular Adnexal Lymphoid T Tumor by Monoclonal Antibodies
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Ophthalmologica
- Vol. 187 (1) , 43-49
- https://doi.org/10.1159/000309300
Abstract
The phenotype of a lymphoid orbital tumor is described, using monoclonal antibodies of the OKT series. The majority of tumor cells lacked surface immunoglobulins and bound OKT3, hence they arose from the T lineage. These cells belonged to the mature helper T cell subpopulation since a great proportion was recognized by OKT4 antibody. In contrast, a decrease in the peripheral blood OKT4+ pool was observed. The results demonstrate the importance of using a panel of markers, such as monoclonal antibodies, for the identification of cell derivation of lymphomas.Keywords
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