Palladium-Catalyzed Synthesis of Stereodefined 4-Arylidene-3 Tosyloxazolidin-2-ones from 2-Propynyl Tosylcarbamates and Unsaturated Halides (or Triflate)

Abstract
2-propynyl tosylcarbamates undergo cyclisation-coupling reactions with aryl iodides (and one alkenyl triflate) in the presence of base and of catalytic amounts of a palladium(0)-phosphine complex to form (E)-4-arylidene or 4-alkylidene-3-tosyloxazolidin-2-ones in a regio- and stereoselective manner.

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