Immunological abnormalities in opsoclonus cerebellopathy
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Neuro-Ophthalmology
- Vol. 5 (4) , 271-275
- https://doi.org/10.3109/01658108509004941
Abstract
Opsoclonus and other cerebellar symptomatology developed in a patient who underwent mastectomy for adenocarcinoma of the breast. No evidence for metastases was found. Immunological studies demonstrated decreased function of T suppressor cells and hyperreactivity of T helper cells in spite of a normal suppressor/ helper ratio. The clinical condition, as well as the immunological abnormalities normalized under steroid treatment. An autoimmune process as etiopathogenesis of this paraneoplastic syndrome is proposed.Keywords
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