Variations in serum complement in the nephrotic syndrome and other forms of renal disease.

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  • 1 July 1958
    • journal article
    • Vol. 1  (3) , 234-50
Abstract
Serial complement determinations have been carried out in 75 patients suffering from various forms of renal disease. Very low serum complement levels were found during the early active stage of acute nephritis, but these low values returned to normal in most cases in parallel with clinical recovery. Moderately depressed complement levels were found in subacute nephritis. These values returned to normal whether clinical recovery occurred or whether the patient progressed to chronic nephritis with or without terminal renal failure. Cases of chronic nephritis, chronic pyelonephritis or of chronic renal damage from other causes gave normal complement values.