CYTOPLASMIC AND CELL-SURFACE STRUCTURE OF PURIFIED LIVER GAP-JUNCTIONS REVEALED BY FREEZE-DRYING

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  • 1 January 1984
    • journal article
    • research article
    • Vol. 33  (1) , 84-89
Abstract
After freeze-drying of purified [mouse] liver gap junction plaques and vesicles, the structural features of the inner and outer aspects of purified gap junctions were investigated. No structural details were seen on the cytoplasmic side of the connections, whereas on the cell surface side the connections were organized in a paracrystalline pattern and exhibited a central depression or pore. The central pore through each connection apparently varies in diameter along its length and the closing site is probably located near the cytoplasmic face.