Human oncogenes
- 1 April 1984
- journal article
- review article
- Published by Springer Nature in Human Genetics
- Vol. 66 (2-3) , 132-142
- https://doi.org/10.1007/bf00286587
Abstract
The information published on human oncogenes up to the fall of 1983 is reviewed. Retroviral oncogenes, protooncogenes, and cellular transforming genes are compared. Transforming genes derived from the ras gene family are described in detail. The different mechanisms of activation of proto-oncogenes are summarized. Finally, the concerted or sequential action of cellular transforming genes in the multistep process of carcinogenesis is discussed.Keywords
This publication has 95 references indexed in Scilit:
- Cancer: Step by step into carcinogenesisNature, 1983
- Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth FactorScience, 1983
- Nucleotide Sequence Analysis of the T24 Human Bladder Carcinoma OncogeneScience, 1983
- Cancer: Chromosome aberrations and oncogenesNature, 1983
- Molecular cloning and nucleotide sequence of a transforming gene detected by transfection of chicken B-cell lymphoma DNANature, 1983
- Onco gen: Human oncogene locations and chromosome aberrationsNature, 1983
- Cellular Transforming GenesScience, 1982
- Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasmsCell, 1982
- Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for OncogenesisScience, 1981
- Transforming activity of DNA of chemically transformed and normal cellsNature, 1980