THE EFFECT OF ANTI-GONADOTROPIC SERA UPON GONADOTROPIC SECRETION IN PARABIOTIC RATS1¹

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Abstract
Anti-gonadotropic sera obtained from 2 adult, [male] rabbits receiving prolonged injs. of an aq., supercentrifuged extract of sheep pituitary, inhibited the effectiveness of the endogenous gonadotropic secretion of the castrate partner''s pituitary in 11 [female]-[female] and 7 [female]-[male] parabiotics when injected into either the castrated or intact partner. The inhibitory sera was of sufficient titer to prevent the ovarian hypertrophy and the extensive luteinization found in the control series.

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