Human apolipoprotein A-I--C-III gene complex is located on chromosome 11.
- 1 March 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis: An Official Journal of the American Heart Association, Inc.
- Vol. 4 (2) , 97-102
- https://doi.org/10.1161/01.atv.4.2.97
Abstract
The genes for two of the apolipoproteins, apo A-I and apo C-III, previously shown to be within 3kb in the genome, were localized to human chromosome 11 by Southern blot analysis of DNA from human-rodent somatic cell hybrids. These two genes were shown to exhibit polymorphisms associated with dyslipoproteinemia and premature atherosclerosis, and it will now be possible to examine the relationship of these genes to the many others that have been assigned to this chromosome.This publication has 56 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Linkage of human apolipoproteins A-I and C-III genesNature, 1983
- Somatic Cell Genetics and Gene FamiliesScience, 1983
- An inherited polymorphism in the human apolipoprotein A-I gene locus related to the development of atherosclerosisNature, 1983
- Polymorphism in the 5′ Flanking Region of the Human Insulin Gene: A Genetic Marker for Non-Insulin-Dependent DiabetesNew England Journal of Medicine, 1983
- Familial Deficiency of Apolipoproteins A-I and C-III and Precocious Coronary-Artery DiseaseNew England Journal of Medicine, 1982
- The insulin gene is located on chromosome 11 in humansNature, 1980
- The UPS locus encoding uroporphyrinogen I synthase is located on human chromosome 11Biochemical and Biophysical Research Communications, 1980
- Regional assignments of the genes for fumarate hydratase and guanylate kinase on chromosome 1 and for lysosomal acid phosphatase and esterase A4 on chromosome 11Cytogenetic and Genome Research, 1976
- Assignments of the human genes for lactate dehydrogenase-A and thymidine kinase to specific chromosomal regionsCytogenetic and Genome Research, 1975