Ultrastructural Changes in Lattice Dystrophy of the Cornea
- 1 January 1975
- journal article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 7 (5) , 321-344
- https://doi.org/10.1159/000264769
Abstract
The ultrastructural changes in lattice dystrophy of the cornea are mainly characterized by stromal changes. (I) Some keratocytes show distinct signs of cellular activity with a more abundant cytoplasm and more organelles, while others show a pronounced degeneration with a cytoplasm containing numerous vesicles of various electron-density. (2) There is a fine fibrillar degeneration, amyloid in nature, with strongly interwoven fine fibrils having 80–100 Å in diameter. (3) In many areas this fine fibrillar degeneration is associated with areas of mottled appearance, probably due to cross-sectioned collagen fibrils in various stages of degeneration.Keywords
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