Studies in electrically induced convulsions in animals.

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Abstract
[longdash]Electrically induced convulsive seizures were produced in cats and rats. When a severe seizure comparable to grand mal resulted, which in its large outlines contained an initial clonus, followed by clonic and/or tonic phases and finally coma, attempts to condition the induced seizure failed. Variations in emotional excitement were produced by air blast stimulation, by inj. of adrenalin, and by inj. of alc. Air blast stimulation and adrenalin had no effect on the amt. of shock required to produce the seizures, but larger doses of alc. tended to raise the animal''s threshold to the shock. Repeated seizures resulted in increasing submissive, passive, and inactive behavior. Implications of the results with respect to some aspects of epilepsy and the use of shock therapy are discussed.

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