Studies in Leukemia

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Abstract
In Swiss mice, injection of cell-free extracts of brain was followed, within 3 months, by the development of lymphoblastic lymphoma in a few inoculated animals. Kidney extracts showed some leukemogenic activity only after the addition of hyaluronidase. Spleen, liver, lung, thymus, lymph node, reproductive organ and mesenteric tumor material did not show leukemogenic activity within the 3 month period. During a 6 month period animals sporadically developed leukemia with certain clinical differences.