HL–A Antigens and Thyrotoxicosis

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Abstract
HL–A phenotypes were determined in 60 patients with primary thyrotoxicosis and in 60 age-sex matched controls living in the same region in order to establish the frequencies of ten HL–A antigens in the two populations. HL–Al was present in 28 patients and 18 controls (X2 = 2.86, P > 0.05). HL–A13 was present in eight patients and only one control (X2 = 4.32, 0.05 > P > 0.025). These findings suggest that HL–A phenotypes may be of value in studies on the aetiology of primary thyrotoxicosis. The statistical significance of these results is discussed as these findings may be due to chance deviations.

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